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|
Variable
|
Taurine (n = 16)
|
Control (n = 16)
|
p-value*
|
|---|
|
APACHEII score
|
|
Day 1
|
14 (12, 17)
|
13 (11, 15)
|
0.34
|
|
Day 14
|
12 (9, 13)
|
13 (9, 14)
|
0.31
|
|
Changes (1, 14)
|
−4 (−6, −1)
|
−1 (− 4, 2)
|
0.05
|
|
p-value¥
|
0.003
|
0.32
| |
|
SOFA score
|
|
Day 1
|
8 (6, 9)
|
8 (6, 9)
|
0.56
|
|
Day 14
|
5 (4, 6)
|
7 (5, 8)
|
0.02
|
|
Changes (1, 14)
|
−3 (−4, −1)
|
−1 (−3, 1)
|
0.06
|
|
p-value¥
|
0.003
|
0.06
| |
|
GCS
|
|
Day 1
|
7 (7, 7)
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7 (7, 8)
|
0.18
|
|
Day 14
|
9 (7, 10)
|
8 (6, 9)
|
0.17
|
|
Changes (1, 14)
|
2 (0, 3)
|
0.0 (−1, 1)
|
0.03
|
|
p-value¥
|
0.002
|
0.30
| |
|
30-day Mortality (N (%))
| | |
0.33
|
|
Yes
|
1 (6.3)
|
4 (25)
| |
|
No
|
15 (93.8)
|
12 (75)
| |
|
Days on mechanical ventilation
|
18 ± 9
|
23 ± 14
|
0.26
|
|
Length of ICU stay
|
22 (17, 31)
|
21 (18, 39)
|
0.96
|
- Values are presented as mean ± SD, median (IQR) or Frequency (percent). Independent Samples T test was used for days on mechanical ventilation, Fisher’s exact test for 30-day mortality and Mann-Whitney U test for others. Within group comparison was made by by Wilcoxon for APACHEII and SOFA scores and GCS. *p-value for comparison between group; ¥ p-value for comparison within group.
